
Director-General of the World Health Organization (WHO), Tedros Adhanom Ghebreyesus at the Global Fund's Eighth Replenishment Summit at Sandton Convection Centre on November 21, 2025 in Sandton, South Africa. The summit marks a pivotal moment to accelerate the fight to end AIDS, TB and malaria, strengthen resilient and sustainable health systems, and build a healthier, safer future for all. Photo Credit: Gallo Images via Getty Images
Health USAGlobal Health Fund’s Top Donor Pledges Billions More
The United States has reaffirmed its role as the largest donor to the Global Fund to Fight AIDS, Tuberculosis and Malaria, pledging $4.6 billion for 2026–28 despite an overall tightening of international aid budgets.
“This commitment shows that we continue to support multilateral action when it aligns with efficiency, innovation and self-reliance,” said a State Department spokesperson, referring to the new America First Global Health Strategy.
The pledge maintains the US as the Fund’s top donor, contributing nearly a third of the $11 billion raised so far toward an $18 billion target. While slightly below recent cycles, the announcement reassures global health programmes amid reductions from other major donors. Under its new strategy, the US is also investing $150 million in Zipline’s medical-delivery drones and partnering with Gilead Sciences to expand access to the HIV prevention drug lenacapavir. The approach aims to pair American innovation with local responsibility, positioning African health systems as self-reliant customers rather than long-term aid recipients.



