A researcher conducts a breast cancer vaccine related experiment in a lab at Cleveland Clinic. Photo Credit: Shawn Green/Cleveland Clinic

Health USA12. November 2021

Vaccine Against the Deadliest Breast Cancer Is in the Works

There will soon be a vaccine to prevent the deadliest form of breast cancer, since researchers based in Cleveland, United States, are about to launch the first human trial testing – giving hope to patients suffering from this fatal cancer.

“Long term, we are hoping that this can be a true preventive vaccine that would be administered to healthy women to prevent them from developing triple-negative breast cancer, the form of breast cancer for which we have the least effective treatments,” says Dr. G. Thomas Budd, of Cleveland Clinic’s Taussig Cancer Institute and principal investigator of the study.

Between 18 and 24 patients recovering from triple-negative breast cancer within the past three years – and at high risk for recurrence – will take part in the trial. Each woman will receive three shots, each two weeks apart. Triple-negative breast cancer doesn’t respond to hormone or targeted drug therapies, hence the need for an effective vaccine. Only a mastectomy can prevent it. The trial should be completed by September 2022, and the team hopes to eventually administer the vaccine to healthy patients who have the gene mutations responsible for triple-negative breast cancer. The vaccine strategy they are developing could potentially be applied to other tumor types like ovarian and endometrial cancers.

Source:
Business Insider

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